Matthew F. Bush
University of Washington | Department of Chemistry | Box 351700 | Seattle, WA 98195-1700
mattbush@uw.edu | https://biophysicalms.org/ | ORCID
Bio
Matt Bush pursued his Ph.D. from 2003-2008 with Evan Williams and Richard Saykally at the University of California, Berkeley. During that time he used infrared laser spectroscopy and Fourier-transform ion cyclotron resonance mass spectrometry to investigate zwitterion formation in gas-phase biomolecules and the structural effects of hydration on biomolecular and multiply charged ions. This training in high-performance mass spectrometry and physical chemistry laid the ground work for his continued pursuits using gas-phase techniques to investigate the structures and interactions of biomolecules. In 2008 he joined the laboratory of Carol Robinson FRS DBE at the University of Cambridge and the University of Oxford, during which time he was a Waters Research Fellow, a Junior Research Fellow of Jesus College, University of Oxford, and developed experimental and analytical frameworks for using ion mobility mass spectrometry experiments to characterize the structures of drug-like molecules, peptides, proteins, and protein complexes. He joined the chemistry faculty at the University of Washington in 2011, where he is also a member of the Department of Biochemistry and the Biological Physics, Structure and Design Program. His research group is focused on developing mass spectrometry based approaches for elucidating the structures, assembly, and dynamics of biological molecules. His group applies these approaches to a wide range of biological systems, with a focus on those involved in protein homeostasis.
Current Positions at the University of Washington
- Associate Professor | Department of Chemistry | 2019–present
- Adjunct Associate Professor | Department of Biochemistry | 2019–present
- Faculty | Biological Physics, Structure & Design Program | 2011–present
- Affiliate | eScience Institute | 2019-present
Previous Positions & Education
- Assistant Professor | Department of Chemistry | University of Washington | 2011–2019
- Adjunct Assistant Professor | Department of Biochemistry | University of Washington | 2014–2019
- Waters Research Fellow | University of Oxford | UK | Advisor: Prof. Carol V. Robinson FRS DBE | 2010–2011
- Postdoctoral Research Associate | University of Cambridge | UK | Advisor: Prof. Carol V. Robinson | 2008–2009
- Ph.D. | Chemistry | University of California | Berkeley | Advisors: Prof. Evan R. Williams & Prof. Richard J. Saykally | 2003-2008
- B.A. | Chemistry | Carleton College | Northfield | MN | 1999-2003
Awards
- Arthur F. Findeis Award for Achievements by a Young Analytical Chemist | 2017
- Eli Lilly Young Investigator Award in Analytical Chemistry | 2014 | Information
- Sloan Research Fellow | Alfred P. Sloan Foundation | 2014 | Information
- Research Award | American Society for Mass Spectrometry | 2013 | Information
- Junior Research Fellow | Jesus College | University of Oxford | UK | 2010–2011
- Waters Research Fellow | 2010–2011
Publications
- Co-author of >70 peer-reviewed publications.
- >7000 citations | H-Index = 45 | Google Scholar
- See lists of recent and earlier publications. View My Bibliography from NIH NCBI.
Professional Service (selected)
- Advancing Mass Spectrometry for Structural Biology and Biophysics Conference Information
- Board (2015–present)
- Organizer of AMS 2021
- American Chemical Society, Division of Analytical Chemistry
- Long-Range Program Planning Committee, Chair (2017-2020)
- Long-Range Program Planning Committee, Member (2015-2020)
- American Society for Mass Spectrometry
- Asilomar Committee (2015–2017)
- Fall Workshop Co-Organizer (2014)
- Ion Mobility MS Interest Group Coordinator (2012–2014)